The Nike Lebron 18 Low Wile E. vs Roadrunner Space Jam (GS) is inspired by Looney Tunes characters Wile E. Coyote and Road Runner, with the left sneaker echoing the earth tones of Wile E. Coyote's makeup and the Swoosh inspired by Wile E satin with the ACME branding.

The right sneaker to take on the Road Runner hue, using different shades of blue and gold accents, with the Swoosh looking like a cloud of dust and seamless overlays with a similar design. Both sneakers feature a rubber sole and Tune Squad branding on the tongue.